We are not able to edit or refresh some of the reports as the buttons are showing grayed out.
Issue happens if there are any security restrictions in accessing the report or user don't have enough permissions to run a report.
Because of which some times, reports may run only from BI launchpad and not from Rich-client or sometimes user will not be able to refresh from both BI launchpad and Rich-client.
Points to check
1. Login into Central Management Console(CMC) with Administrator credentials.
2. Navigate to Users & Groups -> Select Group List -> Right click on the group the user is member off->Customization->Features->Check if the Design Mode Feature Enabled or disabled.
3. Navigate to Folder-> Navigate to the report path -> right click on the report->check user security for view permissions.
p 4. Open the report->On the File tab, Click the Save drop-down menu
b. Click Save as
c. Check the checkbox “ Remove Document Security “
d. Click Save
e. If you are saving in same location as in original file, Pop-up asks if you want to overwrite the file, click Yes
5. Log out completely from BI launch pad or Rich client. And re-login to test